HOW MUCH YOU NEED TO EXPECT YOU'LL PAY FOR A GOOD LSD CRYSTAL

Inside the LSD-bound crystal framework, the aspect chain in the lid residue L209EL2 sorts intensive hydrophobic contacts with equally LSD and surrounding residues in TMs III, IV, and V (Figure 4C). Once the lid moved aside to expose the binding pocket in simulation, many of such contacts broke. We thus hypothesized that L209EL2 functions like a lat